Cynthia's Podcast

Ep. 347 Expanding Perspectives on LDL, Lipids, and LMHRs with Dave Feldman

I am honored to reconnect with Dave Feldman today. Our last encounter was in December 2020, for Episode 128, where we delved deeply into the topic of cholesterol.
Dave is an engineer by profession. He is profoundly clever and commands great respect within the low-carb and keto community due to his willingness to challenge prevailing narratives, encouraging us to explore alternative perspectives on lipid metabolism and reconsider our understanding of LDL, particularly in the context of lean mass hyper-responders like myself.
In our discussion today, we dive into how LDL became so vilified, with Dave shedding light on several crucial research findings. We explain what low-mass hyper-responders are, examine biases and cognitive dissonance, touch on Dave’s new LMHR study, and discuss the Miami Heart study, a longitudinal study of the roles of LDL and plaque burden. We also explore the impact of ApoB and reflect on the essence of science as a pursuit of truth, and Dave shares what lies ahead for himself and his research.
I trust you will find this conversation engaging and thought-provoking.

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Ep. 346 Gut Health: Unveiling the Science of the Microbiome with Dr. Colleen Cutcliffe 

I am delighted to have Dr. Colleen Cutcliffe, the CEO and Co-founder of Pendulum, joining me today.
Dr. Cutcliffe is a proud alumnus of Johns Hopkins, with over 25 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotech. Before starting Pendulum, she was the Senior Manager of Biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals.
In our discussion today, we dive into the emerging science of the gut microbiome, examining the effects of aging, antibiotics, nutrition, stress, travel, and menopause on gut health and discussing how vaginal and C-section deliveries differ in impact. We explore differentiators for various categories of bacteria and the roles of butyrate and fiber, looking at fecal transplants and the difference between probiotics, prebiotics, and post-biotics, and explaining why Akkermansia is an essential bacteria for regulating insulin satiety, fortifying the mucin layer, and facilitating targeted delivery of butyrate. Dr. Cutcliffe also shares her top tips for mitigating the effects of travel on the gut microbiome and offers a special discount for listeners.
I am confident that you will find today’s discussion with Dr. Colleen Cutcliffe engaging and enlightening. Stay tuned to learn how to adjust your lifestyle for a healthier gut microbiome.

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Ep. 345 EMF Awareness: Impact and Protection Strategies with Juraj Kocar 

Today, I have the honor of connecting with Juraj Kocar, the CEO of Somavedic Technologies. Somavedic is a groundbreaking frequency therapy device providing practical and easily accessible solutions for EMF exposure, improved sleep, and energy revitalization.
Juraj is a perpetually optimistic and forward-thinking entrepreneur motivated by a profound passion for developing and expanding products that significantly impact the lives of others, and he is currently propelling his dream project to new levels of success. In our discussion today, we meticulously define the role of EMFs, diving into how they affect our health, discussing proactive protection measures, and sharing strategies for mitigating EMF exposure while traveling. We also explore how the revolutionary Somavedic device works, my experience using it, how to choose the correct model, the effects of structured water, and biohacking strategies that Juraj uses daily.
Join us for an enriching conversation where we provide valuable insights and practical strategies to enhance your health.

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Ep. 344 Lipid Masterclass: A Deep Dive into Our Cardiovascular Needs with Dr. Thomas Dayspring 

Dr. Thomas Dayspring is certified in internal medicine and clinical lipidology. He is a fellow of the American College of Physicians and the National Lipid Association. He joins me today for the second class in our series of Lipid Masterclasses.
In today’s class, Dr. Dayspring shares valuable insights on cardiovascular health and lipid management. We dive into the complexities of cardiovascular disease, focusing on lipoproteins, atherogenesis progression, and its implications on myocardial infarctions (heart attacks). He explains the mechanisms of ApoB invasion into arterial walls and discusses the critical importance of finding competent healthcare providers, particularly for women navigating the perimenopausal to menopausal transition. He also gets into the limitations of bikini medicine, and we tackle pertinent issues surrounding hormone replacement therapy, including potential side effects and clinical observations.
Dr. Dayspring has a wealth of information to share today, and we have several additional masterclasses coming up to follow this class. Be sure to tune in for those episodes.

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Ep. 343 The Autoimmune Cure: Trauma’s Connection to Autoimmunity with Dr. Sara Gottfried

Today, I am delighted to reconnect with Dr. Sara Gottfried, a board-certified physician practicing evidence-based integrative precision and functional medicine. (She last joined me for Episode 211.)
Dr. Gottfried graduated from Harvard and MIT. She is a Clinical Assistant Professor in the Department of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University and the Director of Precision Medicine at the Marcus Institute of Integrative Health. She is also the author of four New York Times best-selling books, including her recent publication, The Autoimmune Cure.
In our discussion today, we discuss the interrelationship between trauma and autoimmunity, highlighting its prevalence, particularly among women. We dive into the impact of trauma, explaining its correlation with autoimmune conditions and demystifying the role of the PINE network (the Psycho Immune Neuro Endocrine system). We explore triggers for perimenopause and menopause, gender differences specific to the changes in immunity and vulnerability in women, the consequences of burnout in various professions, the shortcomings of conventional allopathic methods in addressing mental health and trauma, and immunomodulation, including vitamins, polyphenols, low-dose Naltrexone, and somatic-based therapies.
With Dr. Gottfried’s invaluable insights into crucial health topics, this episode is a must-listen. Stay tuned for more!

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Ep. 342 Understanding Menopause: Hormonal Shifts in Women’s Brains with Dr. Lisa Mosconi

I am delighted and honored today to interview Dr. Lisa Mosconi. She is an Associate Professor of Neuroscience in neurology and radiology at Cornell Medicine and Director of the Women’s BRAIN Initiative and the Alzheimer’s Prevention Clinic at Weill Cornell Medicine, New York Presbyterian Hospital. She is also a globally acclaimed neuroscientist with a Ph.D. in neuroscience and nuclear medicine and the author of the New York Times bestseller The XX Brain and, more recently, The Menopause Brain.
In our conversation, we discuss how women’s brains change during perimenopause and menopause, looking at the significance of puberty, pregnancy, and perimenopause, as well as the lack of medical research on women and medical gaslighting. We explore the concept of bikini medicine and its misconceptions regarding women’s health and hormones alongside the crucial roles of hormones like estradiol, progesterone, and testosterone in our neuroendocrine system. Dr. Mosconi also provides insights into evolving menopausal treatments, including lifestyle interventions.
Dr. Mosconi is an esteemed figure in neuroscience and a prominent voice in women’s health. I am confident you will gain valuable insights and perspectives from my discussion with her today.

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